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drmark -> RE: Stem Cell...are they ethically Christian? (8/25/2008 2:22:44 PM)
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quote:
As such, unlike adult stem cells (except for very rare cases), placental stem cells tend to be pluripotent, which is the desireable part about embryonic stem cells. However, pluripotency is a two-edged sword in that working with ESCs may be quite difficult to regulate their responses toward beneficial properties. Almost every week, another researcher finds that ASCs appear to have much greater capability for differentiation than previously thought. From The Case for Adult Stem Cell Research: quote:
It has been known for about 30 years that stem cells are present in the tissue of the adult, but it was assumed that they could only form cells of a particular tissue. That is, reprogramming them was considered impossible. In recent years, however, pluripotent stem cells were discovered in various human tissues–in the spinal cord, in the brain, in the mesenchyme (connective tissue) of various organs, and in the blood of the umbilical cord. These pluripotent stem cells are capable of forming several cell types–principally blood, muscle, and nerve cells. It has been possible to recognize, select, and develop them to the point that they form mature cell types with the help of growth factors and regulating proteins. This shows that in tissues of the body, adult stem cells possess a much greater potential for differentiation than previously assumed. This knowledge must be brought into the public consciousness with all possible emphasis. If stem cell research were really only meant for therapeutic uses, which it most obviously should be, adult stem cells would promise a very productive research field–and beyond that, a possibility, without moral objection, to discover fundamentals of the dynamics of tissue differentiation. It has become clear from transplantation experiments with animals, that stem cells of a particular tissue can develop into cells of a completely different kind. Thus, bone marrow stem cells have been induced to become brain cells, but also liver cells. Adult stem cells obviously have a universal program for division that is common to all the kinds of tissue stem cells, and makes them mutually interchangeable.
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